An integrated system for identifying Anti-Microbial Peptides (AMPs) with their functional types based on high-throughput transcriptome and proteome data. In recent years, the widespread use of antibiotics has inspired the rapid growth of antibiotic-resistant microorganisms that usually induce critical infection and pathogenesis. However, as the key components of innate immunity, human host defense antimicrobial peptides and proteins (AMPs) play a critical role in warding off invading microbial pathogens. Typical examples are Human γδ T cells produce antimicrobial peptide elafin (dbAMP_00487) which is the major antiviral protein in cervicovaginal lavage fluid. Human Lactoferricin derivatives (dbAMP_04016) shows an inhibitory effect on bacteria and melanoma cells.